Contrave, Naltrexone/Bupropion, 8/90 Mg - 112 Tablets

Product Name

• Contrave, Naltrexone/Bupropion, 8/90 Mg - 112 Tablets

Scientific Name

• Naltrexone Hydrochloride / Bupropion Hydrochloride

Category Of Contrave

• Anti-Obesity Agent

Mechanism Of Action Of Naltrexone/Bupropion

• Naltrexone is an opioid antagonist that modulates the central reward system.
• Bupropion is a norepinephrine and dopamine reuptake inhibitor that affects appetite regulatory pathways in the brain.
• The combination helps to reduce food intake and control cravings, supporting weight loss.

Therapeutic Indications Of Contrave

• Adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of:
• ≥30 kg/m² (obese), or
• ≥27 kg/m² (overweight) in the presence of at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes, or dyslipidemia).

Method Of Administration Of Contrave

• Take orally with food, preferably in the morning and evening.
• Swallow the tablet whole without crushing, chewing, or dividing.
• Follow the dose escalation schedule provided by your doctor to minimize side effects.

Undesirable Side Effects Of Contrave

May cause:

1. Nausea
2. Constipation
3. Headache
4. Dizziness
5. Dry mouth
6. Insomnia
7. Anxiety

Pregnancy & Breastfeeding Precaution While Taking Contrave

• Contraindicated during pregnancy.
• Not recommended during breastfeeding due to potential risks to the infant.

Warnings & Special Precautions While Taking Contrave

• Contraindicated in patients with uncontrolled hypertension, seizure disorders, bulimia, or anorexia nervosa.
• Risk of suicidal thoughts and behaviors, especially at the beginning of treatment or during dose adjustments.
• Monitor blood pressure and mental status regularly.
• Discontinue immediately if serious allergic reactions or seizures occur.

Storage Conditions Of Contrave

• Store below 25°C.
• Keep in the original package, protected from moisture and light.
• Keep out of reach of children.