Product Name

• Divinusmet XR, Dapagliflozin/Metformin, 5/1000 Mg - 60 Tablets

Scientific Name

• Dapagliflozin / Metformin

Category Of Divinusmet XR

• Combination Antidiabetic (SGLT2 Inhibitor + Biguanide)

Mechanism Of Action Of Dapagliflozin / Metformin

• Dapagliflozin inhibits sodium-glucose co-transporter 2 (SGLT2) in the kidneys, reducing glucose reabsorption and increasing its excretion in urine.
• Metformin reduces hepatic glucose production and improves insulin sensitivity, enhancing peripheral glucose uptake.

Therapeutic Indications Of Divinusmet XR

• Indicated for adults with type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycemic control.
• Suitable for patients not adequately controlled on either dapagliflozin or metformin alone.

Method Of Administration Of Divinusmet XR

• Take orally once daily with food to minimize gastrointestinal side effects.
• Swallow tablets whole without crushing or chewing.
• Dose adjustments may be required based on renal function and individual response.

Undesirable Side Effects Of Divinusmet XR

May cause:

1. Genital infections (e.g., fungal infections)
2. Urinary tract infections
3. Nausea
4. Diarrhea
5. Abdominal pain
6. Flatulence
7. Metallic taste
8. Dehydration

Pregnancy & Breastfeeding Precaution While Taking Divinusmet XR

• Not recommended during pregnancy or breastfeeding.
• Use only if the potential benefits justify the potential risks to the fetus or infant.

Warnings & Special Precautions While Taking Divinusmet XR

• Assess renal function prior to initiation and regularly during therapy.
• Not for use in patients with type 1 diabetes or diabetic ketoacidosis.
• Use with caution in patients at risk of dehydration or lactic acidosis.
• Monitor for signs of urogenital infections and gastrointestinal symptoms.

Storage Conditions Of Divinusmet XR

• Store below 30°C in a dry place.
• Keep away from moisture and light.
• Keep out of reach of children.