Product Name

• Resolor 1 Mg - 28 Tablets

Scientific Name

• Prucalopride Tablet

Category Of Resolor Tablets

• Laxative

Mechanism Of Action Of Prucalopride Tablet

• The active substance in Resolor, Prucalopride, is a ‘5-HT4 receptor agonist’. This means that it works like a substance in the body called 5-hydroxytryptamine (5-HT, also known as serotonin) and attaches to receptors for 5-HT in the gut called ‘5-HT4 receptors.
• When 5-HT binds to these receptors, it normally stimulates movement in the gut. In the same way, when Prucalopride attaches to and stimulates these receptors, it increases this movement and allows the bowels to empty faster.

Therapeutic Indications Of Resolor Tablets

• Constipation is generally described as having fewer than three bowel movements a week.
• Though occasional constipation is very common, some people experience chronic constipation that can interfere with their ability to go about their daily tasks. Chronic constipation may also cause people to strain excessively to have a bowel movement

Method Of Administration Of Resolor Tablets

• The recommended dose of Resolor is 2 mg taken once a day. Patients aged over 65 years should start with a 1 mg dose once a day, and this can be increased to 2 mg once a day if needed
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Resolor Tablets

• The most common side effects with Resolor (seen in more than 1 patient in 10) are headache, nausea (feeling sick), diarrhea and abdominal (tummy) pain.

Pregnancy & Breastfeeding Precautions While Taking Resolor Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Non-Pharmacological Treatments & Advice To Reduce Constipation

• Drink more water
• Eat more fiber, especially soluble, non-fermentable fiber
• Exercise more
• Eat probiotic foods or take probiotic supplements
• Bowel habit training.

Warnings & Special Precautions While Taking Resolor Tablets

• Do not use if you are allergic to any ingredients.

Storage Conditions Of Resolor Tablets

• store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

For More Information About Prucalopride

• Ask your physician or pharmacist
• Visit Medscape at Information About Prucalopride
• Visit Drugbank at Information About Prucalopride
• Visit Drugs.com at Information About Prucalopride
• SFDA website