Zoron, 8 Mg - 10 Tablets

Product Name

• Zoron, 8 Mg - 10 Tablets

Scientific Name

• Ondansetron 8 Mg Tablets

Category Of Zoron 8 Mg Tablets

• Anti-emetic Drugs

Mechanism Of Action Of Ondansetron 8 Mg Tablets

• Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

Therapeutic Indications Of Zoron 8 Mg Tablets

• Ondansetron is used to prevent or treat nausea and vomiting induced by chemotherapy or radiotherapy. In addition, it may be used to prevent or treat postoperative nausea and vomiting.

Method Of Administration Of Zoron 8 Mg Tablets

• Treatment and prevention of nausea and vomiting in connection with chemotherapy or Radiotherapy:

1. Adults: 8 mg 1-2 hours before chemotherapy or radiotherapy, followed by 8 mg every 12. hours for up to 5 days. Your doctor may decide to give the first dose as an injection.
2. Elderly: The same dose as for adults.
3. children aged ≥6 months and adolescents:
4. Children (age 2 years and up) and adolescents under the age of 18 years:
5. The dose is individual and depends on the size/surface of the child. Ondansetron is given immediately before chemotherapy as an injection and an oral dosage can be started twelve hours after chemotherapy and be continued for up to 5 days. The total daily dose for adult dose is 32 mg.

• Treatment and prevention of postoperative nausea and vomiting:

1. Adults, prevention and treatment: 16 mg one hour before anesthesia or 8 mg administered one hour before anesthesia followed by an additional 8 mg after 8 and 16 hours. Your doctor may choose to give you the medicine as injections.
2. Elderly, prevention and treatment: There is limited experience with the use of ondansetron for elderly patients. Ondansetron is however tolerated well by patients above 65 years in chemotherapy (please refer to sections above).
3. Use in children aged ≥ 1 month and adolescents: Oral Formulation: Since it’s not investigated whether orally administered ondansetron can be used for prevention or treatment of nausea and vomiting after surgery your doctor may choose to give you the medicine as injections.

• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Zoron 8 Mg Tablets

• Very common side effects (occur in more than 1 of 10 treated): Headache.
• Common side effects (occur in between 1 and 10 of 100 treated): A sensation of reddening, warmth and Constipation.
• Uncommon side effects (occur in between 1 and 10 of 1.000 treated): Seizures. Hiccups, Low blood pressure, irregular heartbeats, chest pain, and slow pulse. Involuntary movements. Involuntary eye movements. Sometimes changes in liver function have been observed.

Pregnancy & Breastfeeding Precautions While Taking Zoron 8 Mg Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Non-Pharmacological Treatments & Advice To Reduce Nausea & Vomiting

• When trying to control nausea:

1. Drink clear or ice-cold drinks.
2. Eat light, bland foods (such as saltine crackers or plain bread).
3. Avoid fried, greasy, or sweet foods.
4. Eat slowly and eat smaller, more frequent meals.
5. Do not mix hot and cold foods.
6. Drink beverages slowly.
7. Avoid activity after eating.
8. Avoid brushing your teeth after eating.
9. Choose foods from all the food groups as you can tolerate them to get adequate nutrition.

• Treatment for vomiting (regardless of age or cause) includes:

1. Drinking gradually larger amounts of clear liquids
2. Avoiding solid food until the vomiting episode has passed
3. Resting
4. Temporarily discontinuing all oral medications, which can irritate the stomach and make vomiting worse

• Take your infant or a child under 6 years old to the doctor if:

1. Vomiting lasts more than a few hours
2. Diarrhea is also present
3. Signs of dehydration occur
4. There is a fever
5. The child hasn't urinated for six hours

Warnings & Special Precautions while Taking Zoron 8 Mg Tablets

• Tell your doctor:

1. if you are hypersensitive to other drugs belonging to the group of selective serotonin (5-HT3)- receptor antagonists (eg. granisetron, dolasetron). It is, in such a case, possible that you are also allergic to ondansetron.
2. if you have stricture of intestines or constipation because you will need special surveillance by your doctor.
3. if you are going to have or recently have had your tonsils removed, because treatment with Ondansetron may hide symptoms of internal bleeding.
4. if you are a heart patient (with arrhythmia or conduction disorders) and are being treated with other medication such as anesthetics, anti-arrhythmic or beta-blockers at the same time, because of the limited experience hereby.
5. if you have liver impairment.
6. if a child receives ondansetron with hepatotoxic chemotherapeutical agents they should be monitored closely for impaired hepatic function.

• Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, natural supplements or vitamins or minerals

Storage Conditions Of Zoron 8 Mg Tablets

• store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

For More Information About Ondansetron

• Ask your physician or pharmacist
• Visit Medscape at Information About Ondansetron
• Visit Drugbank at Information About Ondansetron
• Visit Drugs.com at Information About Ondansetron
• SFDA website