Glados 30 Mg, Reduce Blood Glucose Level - 30 Tablets

Product Name

• Glados 30 Mg, Reduce Blood Glucose Level & Prevent Diabetes Complications - 30 Tablets

Scientific Name

• Pioglitazone 15 Mg Tablets

Category Of Glados 30 Mg Tablets

• Oral Anti-Diabetic Drugs

Mechanism Of Action Of Pioglitazone

• Pioglitazone is a selective agonist at peroxisome proliferator-activated receptor-gamma (PPARγ) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver.4,2 Activation of PPARγ increases the transcription of insulin-responsive genes involved in the control of glucose and lipid production, transport, and utilization.
• Through this mechanism, pioglitazone both enhances tissue sensitivity to insulin and reduces the hepatic production of glucose

Therapeutic Indications Of Glados 30 Mg Tablets

• It is used to lower blood sugar levels in patients with diabetes mellitus type 2 (non-insulin-dependent). It is used when diet and exercising have failed to control your diabetes

Method Of Administration Of Glados 30 Mg Tablets

• Make sure to take your medication as prescribed by your doctor.
• Your doctor will tell you how much to take of this medication and may change doses depending on your response to the medication and other medicines that you are taking.
• Your doctor may recommend additional diabetes medicines to take along with pioglitazone.
• Take a tablet with or without food.
• Swallow the tablet whole with a full glass of water.
• Take a tablet at the same time every day.
• If you are under stress (e.g. infection, accident, fever, or surgery), make sure to talk to your doctor immediately. Your doctor may change the dose of your diabetes medicines if needed.
• It may take around 2 to 3 months for glycemic control to be reached.
• Make sure to follow a healthy diet and exercise program as recommended by your healthcare provider and get your blood sugar levels checked regularly while taking pioglitazone.
• The recommended initial dose is 15 mg or 30 mg orally once daily. Starting dose should not exceed 15 mg once daily in patients with NYHA Class I or II heart failure. Your doctor may increase the dose by increments of 15 mg if glycemic control is not reached
• The maximum dose is 45 mg.
• The effectiveness and safety of this medicine have not been established in children yet.
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Glados 30 Mg Tablets

• Although the following side effects are not common in everyone, some patients may complain from:

1. upper respiratory tract infection
2. infection of the sinuses
3. headache
4. muscle pain
5. pharyngitis (sore throat)
6. laboratory abnormalities
7. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever
8. Signs of liver problems like stomach pain, nausea or vomiting, unusual or unexplained tiredness, dark urine, yellowing of your skin or the whites of your eyes, and loss of appetite.
9. Edema and weight gain.
10. Fractures (most likely to happen in women usually in the upper arm, the hand, or foot)
11. Signs of hypoglycemia (low blood sugar levels) like shaking, tremors, palpitations, sweating, hunger, and dizziness.

Pregnancy & Breastfeeding Precautions While Taking Glados 30 Mg Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
• Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

Non-Pharmacological Treatments & Advice For Diabetic Patients

• All carbohydrates affect blood glucose levels so it’s important to know which foods contain carbohydrates. Choose the healthier foods that contain carbs and be aware of your portion sizes.
• Eat less salt. Eating lots of salt can increase your risk of high blood pressure, which in turn increases the risk of heart diseases and stroke. And when you have diabetes, you’re already more at risk of all of these conditions.
• Eat more fruit and vegetables. This can help you get the vitamins, minerals, and fiber your body needs every day to help keep you healthy.
• You can always try low or zero-calorie sweeteners (also known as artificial sweeteners) to help you cut down sugar for example Steviana Sweetener or Tropicana Slim Sweetener
• Don’t forget to keep moving. Being more physically active goes hand in hand with eating healthier.
• Remember to measure your blood glucose level continuously by using home monitor like Accu-Check, Instant, Blood Glucose Monitor
• Thiozac Capsules & Neurobion Tablets will help you to reduce neuropathy induced by diabetes
• If you experience symptoms of hypoglycemia such as weakness, dizziness, increased sweating, fast heart beating, vision disorders, or difficulty in concentration, it usually helps to eat or drink something containing sugar.

Warnings & Special Precautions while Taking Glados 30 Mg Tablets

• Talk to your doctor or pharmacist if you develop allergic reactions such as shortness of breath, skin rash, swelling of the face or neck, decreased blood pressure, and dizziness
• This medicine may cause fluid retention which can worsen or lead to heart failure. The risk of fluid retention was shown to be higher in patients who are using insulin in combination with this medicine
• Make sure to talk to your doctor before starting this medicine if you have heart problems (e.g. heart failure)
• This medicine may cause edema (swelling) that is dose-related. If this happens, make sure to tell your doctor about it. Your doctor may reduce the dose if needed.
• This medicine may be linked to liver problems that can be fatal.
• This medicine may increase the risk of fractures in female patients.
• This medicine may cause an increased risk of bladder cancer, especially when used for a prolonged time.
• This medicine may cause hypoglycemia (low blood glucose levels) when given with insulin or an insulin secretagogue
• High blood glucose levels may cause macular edema (eye edema). It is recommended that you do regular eye check-ups
• Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medications including over-the-counter non-prescription medicines, prescription medicines, herbal supplements, vitamins, and supplements.

Storage Conditions Of Glados 30 Mg Tablets

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

Normal Ranges

• Random blood sugar test: A blood sample will be taken at a random time. Regardless of when you last ate, a blood sugar level of 200 milligrams per deciliter (mg/dL) or higher suggests diabetes. A blood sugar level of less than 140 mg/dL is normal. A reading between 140 and 199 mg/dL indicates prediabetes
• Fasting blood sugar test. A blood sample will be taken after an overnight fast. A fasting blood sugar level of less than 100 mg/dl is normal. A fasting blood sugar level from 100 to 125 mg/dL is considered prediabetes. If it's 126 mg/dL or higher on two separate tests, you may have diabetes.
• Oral glucose tolerance test: For this test, you fast overnight, and the fasting blood sugar level is measured. Then you drink a sugary liquid, and blood sugar levels are tested periodically for the next two hours.

For More Information About Pioglitazone

• Ask your physician or pharmacist
• Visit SFDA website
• Visit Medscape at Information About Pioglitazone
• Visit Drugs.com at Information About Pioglitazone
• Visit DrugBank at Information About Pioglitazone