Isoptin 80 Mg, Antihypertensive - 50 Tablets

Product Name

• Isoptin, Verapamil Hydrochloride, 80 Mg, Film-Coated Tablets - 50 Tablets

Scientific Name

• Verapamil 80 Mg Tablets

Category Of Isoptin 80 Mg Tablets

• Anti-Hypertensive Drugs

Mechanism Of Action Of Verapamil

• Non-dihydropyridine calcium-channel blocker: Inhibits transmembrane influx of extracellular calcium ions across membranes of myocardial cells and vascular smooth muscle cells without changing serum calcium concentrations, resulting in inhibition of cardiac and vascular smooth muscle contraction and thereby dilating main coronary and systemic arteries

Therapeutic Indications Of Isoptin 80 Mg Tablets

• Hypertension: High blood pressure is a common condition in which the long-term force of the blood against your artery walls is high enough that it may eventually cause health problems, such as heart disease.
• Angina (chest pain)

Method Of Administration Of Isoptin 80 Mg Tablets

• Always take your tablets exactly as your doctor has told you. If you are not sure refer to the label on the carton or check with your doctor or pharmacist.
• Take your tablets with a glass of water. You should swallow the tablets without chewing or crushing them. It does not matter if you have not eaten, so they can be taken with or without food.
• The number of tablets that you will need to take will depend on what you are being treated for
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Isoptin 80 Mg Tablets

• Allergic reactions
• Increased blood sugar levels
• Nervousness
• Headache, dizziness, a tingling or prickling feeling on the skin, tremor
• Movement disorders
• Reduced sense of touch and nerve damage
• Drowsiness
• Vertigo
• A ringing sound in the ears (tinnitus)
• Irregular heartbeat, heart attack, and heart failure
• Low blood pressure
• Flushing of the face or neck
• Burning pain, redness, and swelling of the hands, feet, or other extremities
• Difficulty breathing
• Nausea and vomiting
• Constipation and bowel obstruction
• Swollen gums start to spread over the teeth
• Stomach pain, discomfort, and swelling
• Red or itchy skin rash
• Sensitivity to light
• Hair loss (alopecia)
• Aches and pains in the joints and/or muscles and muscle weakness
• Impotence
• Breast enlargement or swelling
• Breasts that leak milk
• Tiredness
• Increase in liver enzymes
• Greater than normal amounts of prolactin (female hormone) in the blood
• That causes the breasts to produce milk
• Problems with an artificial pacemaker

Pregnancy & Breastfeeding Precautions While Taking Isoptin 80 Mg Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Non-Pharmacological Treatments & Advice To Reduce Blood Pressure

• To measure blood pressure correctly:

1. Don’t eat or drink anything 30 minutes before you take your blood pressure.
2. Empty your bladder before your reading.
3. Sit in a comfortable chair with your back supported for at least 5 minutes before your reading.
4. Put both feet flat on the ground and keep your legs uncrossed.
5. Rest your arm with the cuff on a table at chest height.
6. Make sure the blood pressure cuff is snug but not too tight. The cuff should be against your bare skin, not over clothing.
7. Do not talk while your blood pressure is being measured.

• You will also find the following Non-Pharmacological treatments effective in blood pressure reduction:

1. Lose extra pounds and watch your waistline
2. Exercise regularly
3. Eat a healthy diet
4. Reduce sodium in your diet
5. Quit smoking
6. Cut back on caffeine
7. Reduce your stress
8. Monitor your blood pressure at home and see your doctor regularly

Warnings & Special Precautions while Taking Isoptin 80 Mg Tablets

• Talk to your doctor or pharmacist before taking Isoptin if:

1. you have ever suffered from heart failure, first degree AV block, or an irregular heartbeat
2. you have very low blood pressure
3. you have liver or kidney disease
4. you are being treated with injectable beta-blockers (except in an intensive care situation)
5. you have any neuromuscular diseases e.g. myasthenia gravis, Lambert-Eaton Syndrome, or advanced Duchenne muscular dystrophy

• Tell your doctor or pharmacist if you are taking have recently taken or might take any of the following medicines:

1. beta-blockers used to treat high blood pressure and heart conditions (these include propranolol and metoprolol)
2. alpha-blockers used to treat high blood pressure, heart conditions and prostate disorders (these include prazosin and terazosin)
3. medicines known as “statins” such as atorvastatin, lovastatin, simvastatin used to lower cholesterol levels
4. any other medicine for high blood pressure or an abnormal heartbeat (arrhythmia) such as flecainide, quinidine, digoxin and digitoxin
5. medicines used to treat depression (including the herbal product St John’s Wort), anxiety or psychosis. These may include imipramine, buspirone and lithium.
6. medicines which are known as immunosuppressants such as ciclosporin, sirolimus, everolimus, and tacrolimus. These are used to prevent organ transplant rejection

Storage Conditions Of Isoptin 80 Mg Tablets

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

Normal Ranges

• Normal: Blood pressure numbers of less than 120/80 mm Hg
• Elevated: is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.
• Hypertension Stage 1: is when blood pressure consistently ranges from 130-139 systolic or 80-89 mm Hg diastolic.
• Hypertension Stage 2: is when blood pressure consistently ranges at 140/90 mm Hg or higher.
• Hypertensive crisis: This stage of high blood pressure requires medical attention. If your blood pressure readings suddenly exceed 180/120 mm Hg, wait five minutes and then test your blood pressure again. If your readings are still unusually high, contact your doctor immediately. You could be experiencing a hypertensive crisis.

For More Information About Verapamil

• Ask your physician or pharmacist
• Visit Medscape at Information About Verapamil
• Visit Drugbank at Information About Verapamil
• Visit Drugs.com at Information About Verapamil
• SFDA website