Dexilant 30 Mg - 28 Caps

Product Name

• Dexilant 30 Mg, Reduce Stomach Acidity & Relief Heartburn - 28 Capsules

Scientific Name

• Dexlansoprazole 30 Mg Capsules

Category Of Dexilant 30 Mg Capsules

• Heartburn Drugs

Mechanism Of Action Of Dexlansoprazole

• Hydrochloric acid (HCl) secretion into the gastric lumen is a process regulated mainly by the H (+)/K (+)-ATPase of the proton pump, expressed in high quantities by the parietal cells of the stomach.
• proton pump inhibitor that inhibits the secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium (H+/K+-exchanging ATPase), the “proton pump” of the gastric parietal cell.
• Dexlansoprazole is a member of a class called “proton pump inhibitors”

Therapeutic Indications Of Dexilant 30 Mg Capsules

• Duodenal ulcers (a sore that forms at the beginning of your small intestine)
• H Pylori eradication (bacteria that can live in your gut and cause ulcers) to prevent recurrence of duodenal ulcers
• Benign gastric ulcer (a non-cancerous sore that forms in your stomach)
• NSAID-associated ulcer (sore that forms in your gut due to excessive use of NSAIDs)
• GERD (acid reflux also known as “heartburn”): is the backflow of acid from the stomach into the gullet (“food pipe”) which may become inflamed and painful. This may cause your symptoms such as a painful sensation in the chest rising to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).
• Erosive esophagitis (acid irritation injuring the esophagus): inflammation that may damage tissues of the esophagus, the muscular tube that delivers food from your mouth to your stomach. Esophagitis can cause painful, difficult swallowing and chest pain.
• Pathological hyper-secretory conditions (problems in the gut that cause excessive acid production)

Method Of Administration Of Dexilant 30 Mg Capsules

• Take with or without food
• Swallow whole; do not chew
• Healing of erosive esophagitis: 60 mg once daily for up to 8 weeks
• Maintenance of healed erosive esophagitis: 30 mg once daily for up to 6 months
• Symptomatic non-erosive GERD: 30 mg once daily for 4 weeks
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Dexilant 30 Mg Capsules

• Most commonly reported adverse reactions (≥2%): diarrhea, abdominal pain, nausea, upper respiratory tract infection, vomiting, and flatulence.

Pregnancy & Breastfeeding Precautions While Taking Dexilant 30 Mg Capsules

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Non-Pharmacological Treatments & Advice To Reduce Heartburn

• Eat sparingly and slowly
• Avoid certain foods like (Fried food, Chili foods, …etc.)
• Don't drink carbonated beverages
• Stay up after eating & Finish eating three hours before you go to bed
• Don't move too fast
• Sleep on an incline
• Lose weight if it's advised
• Avoid tight clothes
• If you smoke, quit
• Remember you can always check for H-Pylori Infection by using Heli C Check, H. Pylori Self-Testing Device

Warnings & Special Precautions while Taking Dexilant 30 Mg Capsules

• Do not use this medication in:

1. Patients with known hypersensitivity to any component of the formulation
2. Patients receiving rilpivirine-containing products

• Gastric Malignancy: Symptomatic response with dexlansoprazole does not preclude the presence of gastric malignancy
• Acute Interstitial Nephritis: Observed in patients taking PPIs
• Cyanocobalamin (Vitamin B-12) Deficiency: Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin
• Clostridium difficile Associated Diarrhea: PPI therapy may be associated with increased risk
• Bone Fracture: Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine
• Hypomagnesemia: Reported rarely with prolonged treatment with PPIs
• Interactions with Diagnostic Investigations for Neuroendocrine Tumors: Increases in intragastric pH may result in hypergastrinemia and enterochromaffin-like cell hyperplasia and increased
• chromogranin A levels which may interfere with diagnostic investigations for neuroendocrine tumors
• Interaction with Methotrexate: Concomitant use with PPIs may elevate and/or prolong serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal.
• Tell your doctor or pharmacist if you are taking:

1. Antiretrovirals
2. Warfarin
3. Methotrexate
4. Digoxin
5. Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib,
6. mycophenoloate mofetil, ketoconazole/itraconazole)
7. Tacrolimus
8. CYP2C19 or CYP3A4 Inhibitors
9. CYP2C19 or CYP3A4 Inducers

Storage Conditions Of Dexilant 30 Mg Capsules

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

For More Information About Dexlansoprazole

• Ask your physician or pharmacist
• Visit Medscape at Information About Dexlansoprazole
• Visit Drugbank at Information About Dexlansoprazole
• Visit Drugs.com at Information About Dexlansoprazole
• SFDA website