Motilium 10 Mg - 30 Tablets

Product Name

• Motilium Tablets

Scientific Name

• Domperidone 10 mg Tablets

Category Of Motilium Tablets

• Anti-emetic Drugs

Mechanism Of Action Of Domperidone

• The DA2-receptor antagonist domperidone antagonizes the inhibitory effect of dopamine, resulting in stimulation of gastric muscle contraction. This provides a mechanism for the gastrokinetic effect of domperidone.

Therapeutic Indications Of Motilium Tablets

• Domperidone is used in adults to treat the following symptoms: nausea (feeling sick) and vomiting (being sick), a heavy stomach or bloating, a sensation of discomfort in the stomach area, or when stomach contents flow back into the gullet, as with belching and heartburn.

Method Of Administration Of Motilium Tablets

• Duration of treatment:

1. Symptoms usually resolve with 3-4 days of taking this medicine.
2. Do not take Domperidone Tablets for longer than 7 days without consulting your doctor.

• Route of administration:

1. Swallow the tablets whole with a drink of water.
2. Take the tablets before a meal and, if needed, before you go to bed.

• Unless otherwise prescribed by the doctor, the recommended dose is:

1. Adults and adolescents 12 years of age and older with a bodyweight of 35 kg or more: The usual dose is one tablet taken up to three times per day, if possible before meals. Do not take more than three tablets (corresponding to 30 mg domperidone) per day.
2. Use in children and adolescents from birth to a bodyweight of less than 35 kg: Tablets are not suitable for children weighing less than 35 kg

• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Motilium Tablets

• Rare (may affect up to 1 in 1,000 people):

1. Unusual production of breast milk in men and women
2. Breast enlargement in men
3. Lowering of sexual drive (libido) in men
4. In women, menstrual periods may be irregular or stop
5. Mild stomach cramps
6. Very rare (may affect up to 1 in 10,000 people):
7. An itchy, lumpy rash.
8. A blood test shows changes in the way your liver is working.

Pregnancy & Breastfeeding Precautions While Taking Motilium Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Non-Pharmacological Treatments & Advice To Reduce Nausea & Vomiting

• When trying to control nausea:

1. Drink clear or ice-cold drinks.
2. Eat light, bland foods (such as saltine crackers or plain bread).
3. Avoid fried, greasy, or sweet foods.
4. Eat slowly and eat smaller, more frequent meals.
5. Do not mix hot and cold foods.
6. Drink beverages slowly.
7. Avoid activity after eating.
8. Avoid brushing your teeth after eating.
9. Choose foods from all the food groups as you can tolerate them to get adequate nutrition.

• Treatment for vomiting (regardless of age or cause) includes:

1. Drinking gradually larger amounts of clear liquids
2. Avoiding solid food until the vomiting episode has passed
3. Resting
4. Temporarily discontinuing all oral medications, which can irritate the stomach and make vomiting worse

• Take your infant or a child under 6 years old to the doctor if:

1. Vomiting lasts more than a few hours
2. Diarrhea is also present
3. Signs of dehydration occur
4. There is a fever
5. The child hasn't urinated for six hours

Warnings & Special Precautions while Taking Motilium Tablets

• Do not use the medication if you are:

1. Are allergic (hypersensitive) to domperidone or any of the other ingredients
2. Have stomach bleeding or if you regularly have severe abdominal pain or persistent black stools
3. Have a blocked or perforated gut.
4. Have a tumor of the pituitary gland (prolactinoma).
5. Taking certain medicines that slow down the metabolism (the breaking down) of other medicines in the body and can also affect your heart rhythms such as ketoconazole, fluconazole, or voriconazole, which are used to treat fungal infections; the antibiotics erythromycin, clarithromycin, or telithromycin; or amiodarone, a heart medicine.
6. If you have or have had liver disease.
7. If you have renal disease
8. It is important to ask your doctor or pharmacist when you are taking any other medicines, including medicines obtained without a prescription.

Storage Conditions Of Motilium Tablets

• store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

For More Information About Domperidone

• Ask your physician or pharmacist
• Visit Drugbank at Information About Domperidone
• SFDA website