Dienogest acts as an agonist at the progesterone receptor (PR) with weak affinity that is comparable to that of progesterone but has a very potent progestogenic effect in the endometrium, causing endometrial atrophy after prolonged use.
It promotes anti proliferative, immunologic and antiangiogenic effects on endometrial tissue.
Dienogest reduces the level of endogenous production of oestradiol and thereby suppresses the trophic effects of oestradiol on both the eutopic and ectopic endometrium.
Continuous administration of dienogest results in a hyper progestogenic and moderately hypoestrogenic endocrine environment, which causes initial decidualization of endometrial tissue.
It is an antagonist at androgen receptors, improving androgenic symptoms such as acne and hirsutism.

Indicated for use as the treatment of endometriosis alone and as a contraceptive in combination with ethinylestradiol.

The dosage of Visanne Tablets is one tablet daily without any break, taken preferably at the same time each day with some liquid as needed.
Tablets must be taken continuously without regard to vaginal bleeding.
When a pack is finished the next one should be started without interruption.

Although the following side effects are not common in everyone, some patients may complain from:
headache or migraine
breast discomfort,
hot flushes
mood changes, including depression, irritability, nervousness, problems sleeping, loss of interest in sex
acne, hair loss
nausea, abdominal pain, wind, swollen tummy or vomiting
weight gain
back pain
uterine/vaginal bleeding including spotting
unusual weakness.

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

Eat foods rich in antioxidants.
Antioxidants like folate and zinc may improve fertility for both men and women like : Co Q10
Eat a bigger breakfast.
Avoid trans fats.
Cut down on carbs if you have PCOS.
Eat fewer refined carbs.
Eat more fiber.
Swap protein sources.
Choose high fat dairy.

To avoid becoming pregnant, you should use non-hormonal contraceptive precautions, such as a condom or another barrier method.
You must not use sex-hormone containing contraceptives of any form (tablet, patch, intrauterine system) while taking Visanne Tablets.
Do not use rhythm or temperature methods.
These methods can be unreliable.
If in an exceptional case you should become pregnant during the use of Visanne Tablets, there is a higher likelihood in users of progestogen containing preparations like Visanne Tablets to have an ectopic pregnancy (the embryo develops outside the womb).
Tell your doctor before you start taking Visanne Tablets, if you had an ectopic pregnancy in the past, or have an impaired function of the fallopian tubes.
If you experience unexplained abdominal complaints that are different to the symptoms you commonly experience from your endometriosis, you should contact your doctor immediately because an ectopic pregnancy must be considered.

Store below 25°c
Don’t refrigerate
Keep this medicine out of the sight and reach of children.
Store in the original package to protect from moisture.
Do not use this medicine after the expiry date which is stated on the box/blisters/label.
The expiry date refers to the last day of the month.

Visanne

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