Hydrochloric acid (HCl) secretion into the gastric lumen is a process regulated mainly by the H (+)/K (+)-ATPase of the proton pump, expressed in high quantities by the parietal cells of the stomach.
proton pump inhibitor that inhibits the secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium (H+/K+-exchanging ATPase), the “proton pump” of the gastric parietal cell.
Esomeprazole is a member of a class called “proton pump inhibitors”

Duodenal ulcers (a sore that forms at the beginning of your small intestine)
H Pylori eradication (bacteria that can live in your gut and cause ulcers) to prevent recurrence of duodenal ulcers
Benign gastric ulcer (a non-cancerous sore that forms in your stomach)
NSAID-associated ulcer (a sore that forms in your gut due to excessive use of NSAIDs)
GERD (acid reflux also known as “heartburn”): is the backflow of acid from the stomach into the gullet (“food pipe”) which may become inflamed and painful. This may cause symptoms such as a painful sensation in the chest rising to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).
Erosive esophagitis (acid irritation injuring the esophagus): inflammation that may damage tissues of the esophagus, the muscular tube that delivers food from your mouth to your stomach. Esophagitis can cause pain, difficulty swallowing, and chest pain.
Pathological hyper-secretory conditions (problems in the gut that cause excessive acid production)

Always take this medicine exactly as your doctor or pharmacist has told you.
Check with your doctor or pharmacist if you are not sure.
Your doctor will tell you how many capsules to take and how long to take them. This will depend on your condition and how old you are.
It is recommended that you take your capsules in the morning.
You can take your capsules with food or on an empty stomach.
Swallow your capsules whole with half a glass of water.
Do not chew or crush the capsules. This is because the capsules contain coated pellets that stop the medicine from being broken down by the acid in your stomach. It is important not to damage the pellets.
Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
If you take more than you should, talk to a doctor or go to the hospital straight away.
If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next
Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Like all medicines, this medicine can cause side effects, although not everybody gets them you may suffer from:

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

You we also find the following Non-Pharmacological treatment effective
Eat sparingly and slowly
Avoid certain foods like (Fried food, Chili foods, …etc.)
Don't drink carbonated beverages
Stay up after eating & Finish eating three hours before you go to bed
Don't move too fast
Sleep on an incline
Lose weight if it's advised
Avoid Tight clothes
If you smoke, quit
Remember you can always check for H-Pylori Infection by using Heli C Check, H.Pylori Self-Testing Device

If any of the following happen to you before you start taking Omeprazole or while you are taking it, talk to your doctor straight away:

You lose a lot of weight for no reason and have problems swallowing.
You get stomach pain or indigestion.
You begin to vomit food or blood.
You pass black stools (blood-stained feces).
You experience severe or persistent diarrhea.
You have severe liver problems.
You are due to have a specific blood test (Chromogranin A).
Taking a proton pump inhibitor like Omeprazole, especially for more than one year, may slightly increase your risk of fracture in the hip, wrist, or spine. Tell your doctor if you have osteoporosis or if you are taking corticosteroids (which can increase the risk of osteoporosis)

Tell your doctor or pharmacist if you are taking any of the following medicines used for:

Store below 25°c
Don’t refrigerate
Keep this medicine out of the sight and reach of children.
Store in the original package to protect from moisture.
Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

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